如何规范有效的初次治疗至关重要？这份指南请收好！

, the of is only to and , but the 5-year rate is the , only 39%. Only 20% of are in the , and most of the are in the and late when they are , the of and can only . For some , the may be , for , but this does not mean the is "".

to , 85% of may the , is very , once it , the are very , the is very , and it is to cure.

, how to and is a of to and .

and is !

The is to the 's of life and . In , many have , , or even the and , will lay the for "" and "". , with must at home and to the of the plan.

How to ? this

The of and mid- of is an . , we must take to the of !

1. WAIT AND SEE

In , one is " and wait" for or . That is to say, no will be the , but the year will be in with the 's ; the year will be once six , and the will .

然而，目前常规用于捕捉复发时间点并确定复发类型的方法仍然是CT、PET/CT等影像学检查。对于患者对使用X光检查存在顾虑，担心检查会诱发肿瘤再生的问题，目前尚无明确答案。

此外，当肿瘤小于0.5cm时，传统CT检查难以观察。所以，一旦找到确切的病灶，往往为时已晚，肿瘤已经完全康复复发，甚至扩散到全身！

最新研究表明，血液检测的动态随访和监测可以更准确地发现患者术后复发的趋势和迹象，从而让我们可以选择通过辅助治疗主动预防复发，而不是坐等兔子又等着复发。稍后回复。

血液检测的发展（例如， ）使我们能够提前预测复发的风险。通过检测循环血液中的肿瘤细胞和肿瘤片段（甚至是DNA水平的肿瘤片段），可以获得肿瘤复发的信号。这对于预测早期和中期肺癌手术后的复发风险非常有帮助。目前的州级也在帮助患者通过医疗保险支付验血费用。

CTC（循环肿瘤细胞）检测可以在肿瘤传播的早期检测血液中的CTC。与传统CT检查相比，可提前2-6个月观察肿瘤变化，发出预警信息，发现早期癌症。指导患者用药，有效控制肿瘤进展和转移。想要密切监测血液中循环肿瘤细胞水平的术后患者可以致电全球肿瘤学家网络医疗部申请，或点击了解详情。原文链接：“看血”识癌防复发：肿瘤“捕手”新检测技术，竟能从血液中的癌症种子开始！

Two, take the ! Two to have been for !

A few ago, the and was " and wait", for the to , for the to in the body the army , and then we in a , but for the It's too late. In , with the on , we have more . At , has been and for with and . For , -line can be used for BRCA . with a or to - . can help the time to .

PFS，也称为无进展生存期，是指治疗后达到疾病稳定、部分缓解或完全缓解的时间。从第一个化疗周期到疾病进展计算。据统计，如果不进行维持治疗，每次治疗后复发的时间都会缩短。

目前有 2 种 FDA 批准的用于卵巢癌女性的维持治疗，无论突变状态如何：

1.2018年12月，FDA批准奥拉帕尼用于卵巢癌的一线维持治疗。

The U.S. Food and Drug (FDA) (from ) for the of or or BRCA- (or) , tube or with who have a or to -line - . This is also the time a PARP has been for -line

The is on the of the SOLO-1 III , in PARP the risk of or by 70% with in this , and who and The 3-year -free (PFS) were more than as high, at 60% and 27%, .

2. (), a VEGF, is the for .

, are 3 FDA- of for , -, -, and -line:

(1） with and by as a for -line for III or IV ;

(2） with , or in the of - , the be ≤ 2;

(3） with + or + by as for - .

3. of

is the best in the . The is and can us , , 24 a day. It is an fact that with low are to . For , 's and are in the late of AIDS.

The of is in an , and , and will to the of the body. , the as soon as is the top to and .

免疫功能的调节不仅可以通过饮食、运动等日常生活来实现，还需要临床治疗来帮助我们尽快恢复，比如注射胸腺肽类药物、干扰素、各类细胞免疫恢复免疫功能，恢复免疫杀伤功能。再输液等，如以下免疫细胞的临床辅助治疗，已经进行了大量的临床研究：

1.采用NK细胞疗法

NK细胞又称自然杀伤细胞，是人体免疫细胞家族的重要成员。他们始终奋战在保护人类健康的第一道防线，尤其是在监测和消灭癌细胞的战场上。，因此被称为先天免疫的核心细胞。

在医学上，NK细胞在抗癌的第一道防线中发挥着关键作用。NK细胞具有两种抗癌作用，一种是上述直接杀伤肿瘤细胞，通过释放后穿孔素和颗粒酶或通过死亡受体杀死肿瘤细胞；二是通过分泌细胞因子和趋化因子。调节细胞在免疫系统中的作用、活化T细胞的杀伤作用等。

这些特性使 NK 细胞在肿瘤免疫治疗中大有希望。目前用于肿瘤免疫治疗的 NK 细胞策略包括：体外激活的自体或同种异体 NK 细胞治疗；NK细胞和单克隆抗体（如免疫检查点抑制剂）的组合，以诱导抗体特异性细胞毒性；CAR-NK细胞免疫疗法的构建。

and is on "" NK cell , is to NK from and them into . This has been to be safe and, T-cell , NK do not --host in .

This kind of cell is to the and of NK in the body. 50ml is from , and a very of NK are and then and to the to 1,000 the . 1 to 5 , and then re- into the body, a of NK will 3,000 to 4,000 the body with the , , , , and in the body, so as to . Anti-, and .

目前，中国和美国的NK细胞尚未获批临床使用，但都在积极开展NK细胞治疗实体瘤的临床试验。已广泛用作血液恶性肿瘤临床试验和实体瘤试验中的免疫疗法，包括黑色素瘤、乳腺癌、卵巢癌、神经母细胞瘤、肾细胞癌、结直肠癌和肝细胞癌。此外，作为进入免疫疗法较早的国家，日本是世界上最早批准使用免疫疗法的国家之一。您可以通过全球肿瘤学家网络申请和评估。

在六项卵巢癌临床研究中描述了总共 31 名接受过继转移 NK 细胞的患者。

The of of NK is that of et al., 14 with OC [[59], [60], [61]]. were with and (Cy-Flu), by an of 2.2 x 10 7 NK /kg, and 6 of IL-2 .

, the was well-, with by CT in 4 , in 8, and in 1.

and case to date that NK cell is well and may have a on , but are to NK cell and in vivo .

to the in the , a 60-year-old with who NK cell in was with in 2015, by a of and a huge . with NK , from 11,270 to 580, and all . In , the of the mass on CT scan , and were no side , and is in .

link: NK cell- ( )

good news! U.S. NK in !

2 cell

are the most - in the body so far, and is to T to . , DCs are the of the body's and have a in the of . T in vivo and the of by T . can also the of T and the of T .

from the of and the of co- from cell (OCDC) and from for a of time. The "" that " the line" is to the 's body.

“这个想法是针对肿瘤产生广泛的免疫反应，攻击大量目标。其中一些目标可能只存在于患者自身的肿瘤上，”该研究的合著者 L. 教授说。

图为这一突破性癌症疫苗的研发过程

With this , the the of the cell OCDC. They 25 with , the from , and into -like that play a key role in the in the lab. cell. The then took a of the 's and "fed" the . In this way, the what the like. , the the back into the . , they tell T all the in the , so that the can the and the .

The are just as the . The a rise in - T in , the was ! 25 with III/IV , who had a 2-year rate of 100%. In , who did not had a 2-year rate of only 25%. In , as long as the can the 's , it is to keep away from .

更令人惊讶的是，疫苗奇迹般地治愈了一名患者。这位 46 岁的患者患有 IV 期卵巢癌，通常预后很差。此前，她接受了5轮化疗，均无济于事。或许是抱着死马当活马医的态度，她接受了抗癌疫苗治疗，2年内用了28种个体化抗癌疫苗。在治疗期间，她的癌症得到了很好的控制。停药5年未复发，堪称“临床治愈”！

首次确认！揭示了使 PD-1 更有效的新方法！树突状细胞是最好的帮助！

3 免疫军团特种部队-T 细胞

The of the body on the cell army in the body. As a type of , T have an role. They are the in the body. Once are , T will take the to and kill the . , It is also a " T cell".

T (T , Tc or CTL), also as T , are that and kill when . T have a for with . Once with are , they will T to T to or .

CAR-T疗法的全称是T cell，即嵌合抗原受体T细胞疗法。体外扩增后，将其重新注入患者体内，以识别和攻击自身的肿瘤细胞。原文链接：突破实体瘤不是梦！CAR-T新疗法有望治疗胃癌、胰腺癌等实体瘤！

四、营养支持治疗

and its role in also play a very role: to the , 35% of are to and . , an and a , also out that a diet can the of and by 90%, , , and by 20%. Can by 10%.

In life, also to know what to eat to . Can more , and sea ? In fact, is no to this . The it, or you time that you need a diet and . In fact, it is true that a diet is the for the of the body, the of .

The is:

, eat more - .

, a low-fat diet.

, eat lean .

, your of the , , , and meat.

When for , the of each are , the of , and to the type of from .

Stay away from and open the door to long-term

In to the use of for and to , it is also to have an and anti- .

As a said his own : "In the face of , who can the that they will win, the of and , work with the , try to to the new , and in the . and , and the , can gain hope of and .”

, we can also see that, the same , some are - and have a will to the , and the is much than who from and . . If the is , even the best will not have the .

最后，希望患者能坚定抗癌的信心和决心，为自己打开长期生存的大门！